2010

• Celi L, Hug C, Villaroel M, Clifford G, Mark R. Issues with data mining: predictive modeling on critically ill patients who develop acute renal failure. Crit Care Med, Jan. 2010.
• Celi L, Villaroel M, Davidzon G, Galvin S, Clifford G, Galvin I, Bunton R, Szolovits P. Comparing the performance of customized mortality prediction models using local database against current standard scoring systems. Crit Care Med, Jan. 2010.
• Heldt T. Cardiac output estimation: an engineering perspective. Annual meeting of the Pediatric Academic Societies, Vancouver, CA. May 2010.
• Heldt T. Continuous Cardiac Output Estimation: An Engineering Perspective. Invited presentation, Workshop on Safe and Effective Devices for the Neonatal Intensive Care Unit, 2010 Annual Conference of the Pediatric Academic Societies, Vancouver, BC, Canada (May 2, 2010).
• Heldt T, Verghese GC. Model-based data integration in clinical environments. Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE. 2010, 5209–5212.
• Heldt T, Verghese GC. Multiparameter Data Archiving and Exploration – Implications for Outcome Analysis. Grand Rounds, Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA (April 21, 2010).
• Heldt T, Verghese GC. Integrating Data, Models, and Reasoning in Critical Care. Advanced Technology Applications for Combat Casualty Care (ATACCC) Conference, St. Pete’s Beach, FL, August 2010.
• Heldt T, Kashif FM, O’Leary HM, Suleymanci M, du Plessis AJ, Verghese GC. Comprehensive continuous cerebral oxygen metabolism monitoring through ventilator-gated analysis of cerebral near-infrared spectroscopy. 14th International Conference on Intracranial Pressure and Brain Monitoring, T¨ bingen, Germany, 2010.
• Joshi R, Kshetri K, Lee C-H, Szolovits P. Modeling Latent Pathophysiologic States. NIPS 2010 Workshop on Learning and Planning from Batch Time Series Data. 2010.
• Kashif FM. Non-invasive Cerebrovascular Monitoring. 2010 International Stroke Conference, American Heart Association, San Antonio, TX, USA (February 25, 2010).
• Kashif FM, Heldt T, Novak V, Czosnyka M, Verghese GV. Model-based cerebrovascular monitoring. Model-based cerebrovascular monitoring. Stroke 41: e237, 2010.
• Kashif FM, Heldt T, Novak V, Czosnyka M, Verghese GC. Noninvasive continuous estimation of intracranial pressure: a model-based, patient-specific, and calibration-free approach. 14th International Conference on Intracranial Pressure and Brain Monitoring, Tubingen, Germany, 2010.
• Lojun SL, Sauper CJ, Medow M, Long WJ, Mark RG, Barzilay R. Investigating the impact of age, gender, and social features on resuscitation status in the ICU. AMIA Annu Symp Proc, 2010.
• Mandelbaum T, Scott DJ, Mark RG, Howell MD, Malhutra A, Talmor DS. Outcome of critically ill patients with acute kidney injury using the AKIN criteria. Poster presentation at the Critical Care Canada Forum 2010, November 7-10, 2010, Toronto, Canada, Nov. 2010.
• Ranger M, Heldt T, O’Leary H, Suleymanci M, Johnston C, du Plessis AJ. Description of global cerebral activation during noxious stimulus in critically ill preterm infants. Poster presentation, 8th International Workshop on Pediatric Pain, Mar. 2010.
• Ranger M, Heldt T, O’Leary H, Suleymanci M, Johnston C, du Plessis AJ. Description of global cerebral activation during noxious stimulus in critically ill preterm infants. Poster contribution to the 5th International Workshop on Neonatal Brain Monitoring and Neuroprotection, Jan. 2010.
• Silva I. PhysioNet 2010 Challenge: A robust multi-channel adaptive filtering approach to the estimation of physiological recordings. Comput Cardiol, 37, Sept. 2010.

2009

• Celi LA, Villarroel M, Clifford G, Szolovits P. Local customized mortality prediction modeling for patients with acute kidneyinjury admitted to the intensive care unit. Presentation at the Sixth International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, Genova, Italy (http://cibb09.disi.unige.it), Oct. 2009.
• Celi L, Villaroel M, Davidzon G, Galvin S, Clifford G, Galvin I, Bunton R, Szolovits P. Comparing the performance of customized mortality prediction models using local database against current standard scoring systems. Crit Care Med, 2009. Accepted for publication. Crit Care Med, , Society of Critical Care Medicine’s 39TH Critical Care Congress Abstracts 37(12) Supplement:A1–A567, Dec. 2009.
• Chen T, Clifford GD, Mark RG. The effect of signal quality on six cardiac output estimators. Comput Cardiol, 36:197–200, Sept. 2009.
• Heldt T. Model-based Estimation in Biomedicine. Invited presentation. Workshop on Computational Challenges in Integrative Biological Modeling. Mathematical Biosciences Institute, The Ohio State University, Columbus, Ohio, USA (October 7, 2009).
• Heldt T. Caring for the micro-patient: device needs in the neonatal intensive care unit. Microsystems Technology Laboratory, MIT, Cambridge, MA, March 2009.
• Heldt T, Verghese GC. Cardiac output estimation: a signal processing perspective. Workshop on Safe and Effective Devices for Use in the Neonatal Intensive Care Unit, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, February 2009.
• Kashif FM, Heldt T, Novak V, Czosnyka M, Verghese GV. Non-invasive model-based cerebrovascular monitoring for neurotrauma. Poster presentation, CIMIT Innovation Congress 2009. (Awarded the ”Most Innovative Research Award”), Oct. 2009.
• Moody GB, Lehman LH. Predicting acute hypotensive episodes: The 10th annual PhysioNet/Computers in Cardiology Challenge. Comput Cardiol, 36:541–544, Sept. 2009. (PDF)
• Verghese GC. Getting to the Gray Box: Some Challenges for Model Reduction. Invited Plenary Talk. 2009 American Control Conference, St. Louis, MO, USA (June 10).
• Verghese GC. Deconstructing Integrative Models: The Case for Model Reduction. Invited presentation. Workshop on Computational Challenges in Integrative Biological Modeling. Mathematical Biosciences Institute, The Ohio State University, Columbus, Ohio, USA (October 6, 2009).

2008

• Zong W, Saeed M, and Nielsen L, A vasopressor advisability index for hemodynamic monitoring.
  AMIA Annu Symp Proc. 2008 Nov 6:1198. PubMed ID: 18998959 http://www.ncbi.nlm.nih.gov/pubmed/18998959
  
• Cao H, Eshelman L, Chbat N, Nielsen L, Gross B, Saeed M., Predicting ICU hemodynamic instability using continuous multiparameter trends. Conf Proc IEEE Eng Med Biol Soc. 2008;2008:3803-6.
• Larry J. Eshelman, K. P. Lee, Joseph J. Frassica, Wei Zong, Larry Nielsen, and Mohammed Saeed, Development and Evaluation of Predictive Alerts for Hemodynamic Instability in ICU Patients. AMIA Annu Symp Proc. 2008; 2008: 379–383. Published online 2008.
• Kashif FM, Heldt T, Verghese GC. Model-Based Estimation of Intracranial Pressure and Cerebrovascular Autoregulation, Computers in Cardiology September 2008; 35:369-372.
• Ennett, Colleen M. Lee, K. P. Eshelman, Larry J. Gross, Brian Nielsen, Larry Frassica, Joseph J. Saeed, Mohammed, Predicting respiratory instability in the ICU. Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE. August 2008.
• Khaustov A, Nemati S, Clifford GD. An Open-Source Standard T-Wave Alternans Detector for Benchmarking, Computers in Cardiology September 2008, IEEE Computer Society Press; 35:509-512.
• Clifford GD, Nemati S, Sameni R. An Artificial Multi-Channel Model for Generating Abnormal Electrocardiographic Rhythms , Computers in Cardiology September 2008, IEEE Computer Society Press; 35:773-776.
• Lehman LH, Saeed M, Moody GB, Mark RG. Similarity-Based Searching in Multi-Parameter Time Series Databases, Computers in Cardiology September 2008; 35:653-656.
• Qiao L, Clifford GD. Suppression of false arrhythmia alarms of ICU monitors using heart rate estimation based on arterial blood pressure analysis. 2nd International Conference on Bioinformatics and Biomedical Engineering (iCBBE2008), Shanghai, China. May 16th to 18th, 2008.

2007

• Hug C, Clifford GD.An analysis of the errors in recorded heart rate and blood pressure in the ICU using a complex set of signal quality metrics. Computers in Cardiology September 2007; 34:641-645.
• Lehman LH, Kyaw TH, Clifford GD, Mark RG.A temporal search engine for a massive multi-parameter clinical information database. Computers in Cardiology September 2007; 34:637-640.
• Long WJ. Lessons extracting diseases from discharge summaries. AMIA Annu Symp Proc November 10-14 2007; 478-482.
• Parlikar TA, Heldt T, Ranade GV, Verghese GC. Model-based estimation of cardiac output and total peripheral resistance. Computers in Cardiology 2007; 34:379-382.
• Villarroel M, Saeed A, Clifford GD, Moody GB, Mark RG. Finding relevant cases in large databases of signals, time series, and clinical data. Computers in Cardiology September 2007; 34:265-268.
• Wolfberg AJ, Syed Z, Clifford GD, Tin A, Guttag J, du Plessis AJ. Entropy of fetal EKG associated with intrapartum fever. New England Conference on Perinatal Research October 2007.
• Zhang Y, Silvers CT, Randolph AG.Real-Time Evaluation of Patient Monitoring Algorithms for Critical Care at the Bedside. 29th Annual International Conference of the IEEE on Engineering in Medicine and Biology Society Aug 2007; 2783-2786.
• Zhang Y.Real-Time Development of Patient-Specific Alarm Algorithms for Critical Care. 29th Annual International Conference of the IEEE on Engineering in Medicine and Biology Society Aug 2007; 4351-4354.

2006

• Clifford GD, Villarroel M. Model-based determination of QT intervals. Computers in Cardiology 2006; 33:357-360.
• Clifford GD, Aboukhalil A, Zong W, Sun JX, Janz B, Moody GB, Mark RG. Using the blood pressure waveform to reduce critical false ECG alarms. Computers in Cardiology 2006; 33:829-832.
• Heldt T, Chernyak YB. Analytical solution to minimal cardiovascular model. Computers in Cardiology September 2006; 33:785-788.
• Heldt T, Long W, Verghese GC, Szolovits P, Mark RG. Integrating data, models, and reasoning in critical care. Proceedings of the 28th IEEE EMBS International Conference September 2006; 28:350-353.
• Moody GB, Koch H, Steinhoff U. The PhysioNet/Computers in Cardiology Challenge 2006: QT interval measurement. Computers in Cardiology 2006; 33:313-316.
• Roberts JM, Parlikar TA, Heldt T, Verghese GC. Bayesian networks for cardiovascular monitoring. Proceedings of the 28th IEEE Engineering in Medicine and Biology Conference 2006; 205-209.
• Saeed M, Mark RG. A novel method for the efficient retrieval of similar multiparameter physiologic time series using Wavelet-based symbolic representations. AMIA Annu Symp Proc 2006; 679-683.
• Sun JX, Reisner AT, Mark RG. A signal abnormality index for arterial blood pressure waveforms. Computers in Cardiology September 2006; 33:13-16.
• Zong W, Saeed M, Heldt T. A QT interval detection algorithm based on ECG curve length transform.Computers in Cardiology 2006; 33:377-380.
• Sibanda T, He T, Szolovits P, , Uzuner O. Syntactically-informed semantic category recognizer for discharge summaries. Proceedings of the Fall Symposium of the American Medical Informatics Association AMIA November 2006; 714-718.

2005

• Clifford GD, McSharry PE. Method to filter ECGs and evaluate clinical parameter distortion using realistic ECG model parameter fitting. Computers in Cardiology 2005; 32:715-718.
• Clifford GD, Zapanta L, Janz BA, Mietus J, Mark RG. Segmentation of 24-hour cardiovascular activity using ECG-based sleep/sedation and noise metrics. Computers in Cardiology 2005; 32:595-598.
• Douglass M, Clifford GD, Reisner A, Long WJ, Moody GB, Mark RG. De-identification algorithm for free-text nursing notes . Computers in Cardiology 2005; 32:341-344.
• Heldt T, Mark RG. Understanding post-spaceflight orthostatic intolerance: a simulation study. Computers in Cardiology 2005; 32:631-634.
• Janz BA, Saeed M, Frassica J, Clifford GD, Mark RG. Development and optimization of a critical care alert and display (CCAD) system using retrospective ICU databases.AMIA Annu Symp Proc 2005; .
• Janz BA, Clifford GD, Mark RG. A multivariable analysis of sedation, activity and agitation in critically ill patients using the Riker scale, ECG, blood pressure and respiratory rate. Computers in Cardiology 2005; 32:735-738.
• Janz BA, Frassica J, Baker C, Clifford GD, Mark RG. A new paradigm for managing information in the ICU in response to the 80 hour work week. New England Surgical Society 2005; 86:118-119.
• Long WJ. Extracting diagnoses from discharge summaries. AMIA Annu Symp Proc October 22-26 2005; 470-474.
• McSharry PE, Clifford GD. A Statistical model of the sleep-wake dynamics of the cardiac Rhythm. Computers in Cardiology 2005; 32:591-594.
• Parlikar TA, Verghese GC. A simple cycle-averaged model for cardiovascular dynamics. Proceedings of the 27th Annual IEEE Engineering in Medicine and Biology Society Conference 2005; 27:5490-5494.
• Samar Z, Heldt T, Verghese G, Mark R. Model-based cardiovascular parameter estimation in the intensive care unit. Computers in Cardiology 2005; 32:635-638.
• Sun JX, Reisner AT, Saeed M, Mark RG. Estimating cardiac output from arterial blood pressure waveforms: a critical evaluation using the MIMIC II database. Computers in Cardiology September 2005; 32:295-298.

2004

• Abdala OT, Clifford GD, Saeed M, Reisner A, Moody GB, Henry I, Mark RG. The Annotation Station: an open-source technology for annotating large biomedical databases. Computers in Cardiology 2004; 31:681-685.
• Abdala OT, Saeed M. Estimation of missing values in clinical laboratory measurements of ICU patients using a weighted K-nearest neighbors algorithm. Computers in Cardiology 2004; 31:693-696.
• Ali W, Eshelman L, Saeed M. Identifying artifacts in arterial blood pressure using morphogram variability. Computers in Cardiology September 2004; 31:697-700.
• Clifford GD, McSharry PE. A realistic coupled nonlinear artificial ECG, BP, and respiratory signal generator for assessing noise performance of biomedical signal processing algorithms. Proc of SPIE International Symposium on Fluctuations and Noise 2004; 5467(34):290-301.
• Clifford GD, McSharry PE. A nonlinear artificial model for generating realistic correlated ECG, BP and respiration. 17th international EURASIP conference June 2004; 358-360. Biosignal 2004, Brno, Czech Republic.
• Clifford GD, McSharry PE. Generating 24-hour ECG, BP and respiratory signals with realistic linear and nonlinear clinical characteristics using a nonlinear model. Computers in Cardiology 2004; 31:709-712.
• Douglass M, Clifford GD, Reisner A, Moody GB, Mark RG. Computer-assisted de-identification of free text in the MIMIC II database. Computers in Cardiology 2004; 31:341-344.
• Healey J, Clifford GD, Kontothanassis L, McSharry PE. An open-source method for simulating atrial fibrillation using ECGSYN . Computers in Cardiology 2004; 31:425-427.
• Heldt T, Mark RG. Scaling cardiovascular parameters for population simulations. Computers in Cardiology 2004; 31:133-136.
• McSharry PE, Clifford GD. A comparison of nonlinear noise reduction and independent component analysis using a realistic dynamical model of the electrocardiogram. Proc of SPIE International Symposium on Fluctuations and Noise 2004; 5467(09):78-88.
• McSharry PE, Clifford GD. Open-source software for generating electrocardiogram signals. ARXIV preprints 2004; 0406017.
• Moody GB. Spontaneous termination of atrial fibrillation: a challenge from PhysioNet and Computers in Cardiology 2004. Computers in Cardiology 19-22 Sept. 2004; 31:101-104.
• Nam DS, Youn CH, Lee BH, Clifford GD, Healey J. QoS-constrained resource allocation for a Grid-based multiple source electrocardiogram application . Lecture Notes in Computer Science 2004; 3043:352-359. Information Systems and Information Technologies (ISIT) Workshop, (Grid Session).
• Shu J, Clifford GD, Saeed M, Long WJ, Moody GB, Szolovits P, Mark RG. An open-source, interactive Java-based system for rapid encoding of significant events in the ICU using the Unified Medical Language System. Computers in Cardiology 2004; 31:197-200.
• Wang H, Azuaje F, Clifford GD, Jung B, Black N. Methods and tools for generating and managing ecgML-based information. Computers in Cardiology 2004; 31:573-576.
• Youn CH, Nam DS, Kim B, An ES, Lee BH, Shim EB, Clifford GD. QoS quorum-constrained resource management in wireless grid. Lecture Notes in Computer Science 2004; 3222:65-72.Network and Parallel Computing, (NPC 2004), IFIP International Conference, Wuhan, China, October 18-20.
• Youn CH, Kim B, Nam DS, Shim EB, Clifford GD, Healey J. Resource reconfiguration scheme based on temporal quorum status estimation in computational grids. Lecture Notes in Computer Science 2004; 699-707.

2003

• Chen JJS, Heldt T, Verghese GC, Mark RG. Analytical solution to simplified circulatory model using piecewise linear elastance. Computers in Cardiology 2003; 30:45-48.
• Heldt T, Chang JL, Verghese GC, Mark RG.Cycle-averaged models of cardiovascular dynamics. Modelling and Control in Biomedical Systems 2003; 387-391.
• Heldt T, Oefinger MB, Hoshiyama M, Mark RG. Circulatory response to passive and active changes in posture. Computers in Cardiology September 2003; 30:263-266.
• Long WJ. Parsing free text nursing notes. AMIA Annu Symp Proc November 8-12 2003; 917.
• Moody GB, Jager F. Distinguishing ischemic from non-ischemic ST changes: the PhysioNet/Computers in Cardiology Challenge 2003. Computers in Cardiology 2003; 30:235-237. ISSN 0276-6547.
• Szolovits P. Adding a medical lexicon to an English parser. AMIA Annu Symp Proc November 8-12 2003; 639-643.
• Zong W, Heldt T, Moody GB, Mark RG. An open-source algorithm to detect onset of arterial blood pressure pulses. Computers in Cardiology 2003; 30:259-262.
• Zong W, Moody GB, Jiang D. A robust open-source algorithm to detect onset and duration of QRS complexes. Computers in Cardiology 2003; 30:737-740.

2002

• Saeed M, Lieu C, Raber G, Mark RG. MIMIC II: A Massive Temporal ICU Patient Database to Support Research in Intelligent Patient Monitoring.Computers in Cardiology 2002; 29:641-644